Guillermo Garcia-Manero Selected Research

Chromosome Aberrations (Chromosome Abnormalities)

1/2022	Prediction of survival with intensive chemotherapy in acute myeloid leukemia.
1/2022	Prediction of early (4-week) mortality in acute myeloid leukemia with intensive chemotherapy.
1/2018	Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors.
1/2018	Results of second salvage therapy in 673 adults with acute myelogenous leukemia treated at a single institution since 2000.
11/2017	Clonal chromosomal abnormalities appearing in Philadelphia chromosome-negative metaphases during CML treatment.
3/2017	Poor outcomes associated with +der(22)t(9;22) and -9/9p in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia receiving chemotherapy plus a tyrosine kinase inhibitor.
2/2013	Significance of persistent cytogenetic abnormalities on myeloablative allogeneic stem cell transplantation in first complete remission.
6/2011	Persistence of cytogenetic abnormalities at complete remission after induction in patients with acute myeloid leukemia: prognostic significance and the potential role of allogeneic stem-cell transplantation.
1/2011	NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes.
3/2009	Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia.

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Guillermo Garcia-Manero Research Topics

Disease

183	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2022 - 01/2002
176	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2022 - 01/2002
116	Neoplasms (Cancer) 12/2022 - 07/2002
101	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2022 - 04/2002
77	Leukemia 09/2022 - 02/2002
60	Philadelphia Chromosome 09/2022 - 04/2002
55	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2022 - 07/2002
26	Anemia 01/2022 - 04/2002
26	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2022 - 04/2003
22	Thrombocytopenia (Thrombopenia) 01/2022 - 09/2002
21	Hematologic Neoplasms (Hematological Malignancy) 01/2022 - 07/2002
17	Chromosome Aberrations (Chromosome Abnormalities) 01/2022 - 05/2002
17	Blast Crisis (Blast Phase) 01/2021 - 05/2002
16	Primary Myelofibrosis (Myelosclerosis) 12/2021 - 03/2003
15	Acute Promyelocytic Leukemia 01/2022 - 09/2004
14	Residual Neoplasm 01/2021 - 01/2009
14	Pathologic Complete Response 11/2020 - 12/2003
13	Infections 01/2022 - 03/2003
13	Exanthema (Rash) 01/2021 - 03/2003
13	Diarrhea 01/2020 - 08/2002
12	Neutropenia 10/2021 - 06/2003
11	Myeloid Leukemia (Leukemia, Myelocytic) 01/2021 - 03/2003
10	Fatigue 01/2021 - 04/2003
9	Disease Progression 01/2022 - 05/2002
9	Nausea 01/2020 - 05/2004
8	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 04/2003
7	Pneumonia (Pneumonitis) 01/2022 - 01/2004
6	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 01/2014
6	Leukocytosis (Pleocytosis) 01/2022 - 12/2003
6	Lymphoma (Lymphomas) 01/2021 - 04/2006
6	Fibrosis (Cirrhosis) 10/2018 - 10/2009
6	Splenomegaly 01/2018 - 10/2004
5	Cytopenia 12/2018 - 05/2006
5	Mucositis 10/2017 - 08/2002
4	Hyperbilirubinemia 01/2022 - 03/2003

Drug/Important Bio-Agent (IBA)

60	Imatinib Mesylate (Gleevec)FDA Link 01/2020 - 05/2002
56	Cytarabine (Cytosar-U)FDA LinkGeneric 11/2022 - 05/2002
53	Decitabine FDA Link 01/2022 - 08/2003
52	Azacitidine (5 Azacytidine)FDA Link 12/2022 - 07/2007
43	Tyrosine Kinase InhibitorsIBA 09/2022 - 09/2003
23	Pharmaceutical PreparationsIBA 01/2022 - 04/2003
21	Lenalidomide (CC 5013)FDA Link 10/2022 - 03/2008
21	Histone Deacetylase InhibitorsIBA 01/2020 - 08/2006
20	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 08/2021 - 08/2002
19	Dasatinib (BMS 354825)FDA Link 05/2022 - 12/2007
19	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
19	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 04/2003
18	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 06/2002
17	venetoclaxIBA 11/2022 - 01/2018
15	Clofarabine (Clolar)FDA Link 01/2021 - 10/2003
14	fludarabineIBA 01/2022 - 03/2003
13	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 04/2003
12	Arsenic Trioxide (Trisenox)FDA Link 01/2022 - 09/2004
12	Gemtuzumab (Mylotarg)FDA Link 01/2022 - 01/2002
12	Core Binding Factors (Core-Binding Factor)IBA 01/2022 - 12/2008
12	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 04/2003
11	ponatinibIBA 09/2022 - 11/2015
11	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022 - 04/2004
11	Phosphotransferases (Kinase)IBA 01/2019 - 12/2007
11	Interferon-alpha (Interferon Alfa)IBA 06/2012 - 04/2002
10	Rituximab (Mabthera)FDA Link 01/2022 - 04/2003
9	Biomarkers (Surrogate Marker)IBA 12/2022 - 07/2011
9	Immune Checkpoint InhibitorsIBA 12/2022 - 01/2018
9	Hemoglobins (Hemoglobin)IBA 11/2021 - 04/2002
9	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2009
9	InterferonsIBA 01/2021 - 06/2003
8	Biological ProductsIBA 05/2022 - 02/2006
7	blinatumomabIBA 09/2022 - 12/2017
7	ruxolitinibIBA 11/2021 - 03/2015
7	IronIBA 10/2020 - 07/2006
7	nilotinib FDA Link 01/2020 - 12/2007
7	Sorafenib (BAY 43-9006)FDA Link 11/2019 - 04/2010
7	Prednisone (Sone)FDA LinkGeneric 12/2018 - 10/2009
6	AnthracyclinesIBA 05/2022 - 08/2002
6	Monoclonal AntibodiesIBA 01/2021 - 06/2006
6	Inotuzumab OzogamicinIBA 01/2021 - 03/2015
6	Transaminases (Aminotransferases)IBA 01/2020 - 02/2015
6	Valproic Acid (Depakote)FDA LinkGeneric 02/2015 - 11/2006
6	Vorinostat FDA Link 12/2012 - 02/2008
5	Cladribine FDA LinkGeneric 11/2022 - 08/2005
5	CreatinineIBA 01/2022 - 12/2018
5	fms-Like Tyrosine Kinase 3IBA 01/2022 - 11/2016
5	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2021 - 04/2009
5	cc-486IBA 01/2021 - 01/2015
5	HomoharringtonineIBA 01/2019 - 04/2002
5	Reticulin (Reticular Fiber)IBA 10/2018 - 10/2009
5	Methotrexate (Mexate)FDA LinkGeneric 02/2016 - 04/2003
5	TransferasesIBA 11/2007 - 03/2003
4	luspaterceptIBA 11/2022 - 01/2020

Therapy/Procedure

227	Therapeutics 12/2022 - 04/2002
65	Drug Therapy (Chemotherapy) 05/2022 - 03/2003
19	Stem Cell Transplantation 10/2021 - 09/2002
15	Induction Chemotherapy 07/2022 - 02/2004
14	Salvage Therapy 01/2021 - 04/2003
7	Hematopoietic Stem Cell Transplantation 01/2021 - 12/2010
6	Drug Tapering 11/2021 - 06/2003
5	Transplantation 01/2022 - 10/2007
4	Radiotherapy 10/2022 - 07/2012
4	Homologous Transplantation 01/2022 - 05/2009
4	Erythrocyte Transfusion 12/2021 - 01/2016